AOS1 Antibody

Catalog Number:

33506

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UBE0
NCBI Gene ID: 10055

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human AOS1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AOS1 protein.

Applications:

WB IF

Background:

The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Yoshiaki Azuma, FASEB J, Jun 2001; 10.1096.
Walter Makous, Invest. Ophthalmol. Vis. Sci., Sep 2006; 47: 4160 - 4167.
Hsin-Pei Shih, J. Cell Sci., Mar 2002; 115: 1259.
Thomas Buschmann, J. Biol. Chem., Oct 2001; 276: 40389 - 40395.

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF