TIMP3 Antibody

Catalog Number:

33504

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P35625
NCBI Gene ID: 7078

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TIMP3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TIMP3 protein.

Applications:

WB

Background:

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

Uria J.A., Cancer Res. 54:2091-2094(1994).
Wilde C.G., DNA Cell Biol. 13:711-718(1994).
Silbiger S.M., Gene 141:293-297(1994).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF