Product Datasheet  
TIMP3 Antibody  
Catalog Number: 33504  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P35625
    NCBI Gene ID: 7078
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human TIMP3.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Metalloproteinase inhibitor 3 [Precursor]; TIMP-3; Tissue inhibitor of metalloproteinases 3; Protein MIG-5; TIMP3
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total TIMP3 protein.
  • Applications：  
  • WB
  • Background：  
  • Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

    Uria J.A., Cancer Res. 54:2091-2094(1994).
    Wilde C.G., DNA Cell Biol. 13:711-718(1994).
    Silbiger S.M., Gene 141:293-297(1994).



 
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