TIMP2 Antibody

Catalog Number:

33503

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P16035
NCBI Gene ID: 7077

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human TIMP2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TIMP2 protein.

Applications:

WB IF

Background:

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

Dominique Trudel, AACR Meeting Abstracts, Mar 2004; 2004: 264.
O. Alcazar, Invest. Ophthalmol. Vis. Sci., May 2007; 48: 5057.
Isabelle Kazes, Blood, Nov 2000; 96: 3064 - 3069.
Georgina S. Butler, J. Biol. Chem., Jan 1998; 273: 871.

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF