Product Datasheet  
TIMP2 Antibody  
Catalog Number: 33503  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P16035
    NCBI Gene ID: 7077
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human TIMP2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

    Immunofluorescence: 1:100~1:500
  • other_names：  
  • tissue inhibitor of metalloproteinase 2;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total TIMP2 protein.
  • Applications：  
  • WB IF
  • Background：  
  • Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

    Dominique Trudel, AACR Meeting Abstracts, Mar 2004; 2004: 264.
    O. Alcazar, Invest. Ophthalmol. Vis. Sci., May 2007; 48: 5057.
    Isabelle Kazes, Blood, Nov 2000; 96: 3064 - 3069.
    Georgina S. Butler, J. Biol. Chem., Jan 1998; 273: 871.




 
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