Synuclein-pan Antibody

Catalog Number:

33495

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P37840
NCBI Gene ID: 6622

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human synuclein.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Synuclein protein.

Applications:

WB IHC

Background:

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Eirene Kontopoulos, Hum. Mol. Genet., Oct 2006; 15: 3012 - 3023.
Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569.
Wanli W. Smith, J. Neurosci., Jun 2005; 25: 5544 - 5552.
Yuxin Fan, Hum. Mol. Genet., Oct 2006; 15: 3002 - 3011.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF