Product Datasheet  
Synuclein-pan Antibody  
Catalog Number: 33495  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P37840
    NCBI Gene ID: 6622
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human synuclein.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • NACP; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; SYN; SYUA
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Synuclein protein.
  • Applications：  
  • WB IHC
  • Background：  
  • May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

    Eirene Kontopoulos, Hum. Mol. Genet., Oct 2006; 15: 3012 - 3023.
    Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569.
    Wanli W. Smith, J. Neurosci., Jun 2005; 25: 5544 - 5552.
    Yuxin Fan, Hum. Mol. Genet., Oct 2006; 15: 3002 - 3011.




 
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