Synuclein γ Antibody

Catalog Number:

33493

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O76070
NCBI Gene ID: 6623

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human synuclein γ.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total synuclein γ protein.

Applications:

WB IHC

Background:

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases By similarity. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway By similarity.

Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569.
Anja Leona Biere, J. Biol. Chem., Oct 2000; 275: 34574.
Natalia Ninkina, Mol. Cell. Biol., Nov 2003; 23: 8233 - 8245.
Zhong-Zong Pan, J. Biol. Chem., Sep 2002; 277: 35050 - 35060.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF