Product Datasheet
Synuclein γ Antibody
Catalog Number: 33493
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O76070
NCBI Gene ID: 6623
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human synuclein γ.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- BCSG1; PERSYN; BREAST CANCER-SPECIFIC GENE 1;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total synuclein γ protein.
- Background:
- Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases By similarity. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway By similarity.
Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569.
Anja Leona Biere, J. Biol. Chem., Oct 2000; 275: 34574.
Natalia Ninkina, Mol. Cell. Biol., Nov 2003; 23: 8233 - 8245.
Zhong-Zong Pan, J. Biol. Chem., Sep 2002; 277: 35050 - 35060.
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