RIT1 Antibody

Catalog Number:

33482

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q92963
NCBI Gene ID: 6016

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human RIT1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RIT1 protein.

Applications:

WB

Background:

Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.

Manabu Furukawa, Mol. Cell. Biol., Nov 2000; 20: 8185 - 8197.
Angus Chen, J. Biol. Chem., May 2000; 275: 15432.
Kenneth Wu, Mol. Cell. Biol., Feb 2000; 20: 1382 - 1393.
Kenneth Wu, J. Biol. Chem., Jan 2002; 277: 516 - 527.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF