Product Datasheet  
RIT1 Antibody  
Catalog Number: 33482  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q92963
    NCBI Gene ID: 6016
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human RIT1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • GTP-binding protein Rit1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIBB; RIT
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total RIT1 protein.
  • Applications：  
  • WB
  • Background：  
  • Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.

    Manabu Furukawa, Mol. Cell. Biol., Nov 2000; 20: 8185 - 8197.
    Angus Chen, J. Biol. Chem., May 2000; 275: 15432.
    Kenneth Wu, Mol. Cell. Biol., Feb 2000; 20: 1382 - 1393.
    Kenneth Wu, J. Biol. Chem., Jan 2002; 277: 516 - 527.




 
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