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p50 Dynamitin Antibody

Catalog Number:

33461
other_names: 50 kDa dynein-associated polypeptide; DCT2; DCTN-50; DCTN2; dynactin complex 50 kDa subunit

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q13561
NCBI Gene ID: 10540

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human p50 dynamitin.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total p50 dynamitin protein.

Applications:

WB

Background:

Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

Scott S. Grieshaber, J. Cell Sci., Sep 2003; 116: 3793.
Janis K. Burkhardt, J. Cell Biol., Oct 1997; 139: 469.
Karin A. Melkonian, J. Biol. Chem., Apr 2007; 10.1074.
Lili Yue, J. Biol. Chem., Jul 2000; 275: 23948.

References:

appl_detail:

Western blotting: 1:500~1:3000

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