Product Datasheet  
p50 Dynamitin Antibody  
Catalog Number: 33461  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q13561
    NCBI Gene ID: 10540
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human p50 dynamitin.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • 50 kDa dynein-associated polypeptide; DCT2; DCTN-50; DCTN2; dynactin complex 50 kDa subunit
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total p50 dynamitin protein.
  • Applications：  
  • WB
  • Background：  
  • Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

    Scott S. Grieshaber, J. Cell Sci., Sep 2003; 116: 3793.
    Janis K. Burkhardt, J. Cell Biol., Oct 1997; 139: 469.
    Karin A. Melkonian, J. Biol. Chem., Apr 2007; 10.1074.
    Lili Yue, J. Biol. Chem., Jul 2000; 275: 23948.




 
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