p18 INK Antibody

Catalog Number:

33458

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P42773
NCBI Gene ID: 1031

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human p18 INK antibody.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total p18 INK protein.

Applications:

WB IHC

Background:

Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.

Youzhong Yuan, Cancer Res., Jan 2006; 66: 343 - 351.
A. Koenig, Vet. Pathol., Jul 2002; 39: 458.
Pei-Fang Hung, Am J Physiol Cell Physiol, May 2005; 288: C1094 - C1108.
Mana Mirjany, J. Pharmacol. Exp. Ther., May 2002; 301: 494.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF