Product Datasheet  
p18 INK Antibody  
Catalog Number: 33458  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P42773
    NCBI Gene ID: 1031
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human p18 INK antibody.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • OTTHUMP00000046546; p18(INK4C); p18-INK4C; CDK6 inhibitor p18; cyclin-dependent inhibitor
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total p18 INK protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.

    Youzhong Yuan, Cancer Res., Jan 2006; 66: 343 - 351.
    A. Koenig, Vet. Pathol., Jul 2002; 39: 458.
    Pei-Fang Hung, Am J Physiol Cell Physiol, May 2005; 288: C1094 - C1108.
    Mana Mirjany, J. Pharmacol. Exp. Ther., May 2002; 301: 494.




 
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