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OCT3 Antibody

Catalog Number:

33454
other_names: 41915; OCT4; OTF3; OTF4; OCTAMER-BINDING TRANSCRIPTION FACTOR 3

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q01860
NCBI Gene ID: 5460

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human OCT3 antibody.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total OCT3 protein.

Applications:

WB IHC

Background:

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Y Saijoh, Genes Cells, Feb 1996; 1: 239 - 252.
Christopher L. Shaffer, Drug Metab. Dispos., Apr 2007; 10.1124.
Brian Boer, Nucleic Acids Res., Mar 2007; 35: 1773 - 1786.
E Pikarsky, Mol. Cell. Biol., Feb 1994; 14: 1026 - 1038.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

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