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OCT2 Antibody

Catalog Number:

33453
other_names: 41914; OTF2; OCTAMER-BINDING TRANSCRIPTION FACTOR 2; OTF LYMPHOID-SPECIFIC 2;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P09086
NCBI Gene ID: 5452

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human OCT2 antibody.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total OCT2 protein.

Applications:

WB IF

Background:

Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.

Saleh A. Bakheet, Toxicol. Sci., Feb 2007; 95: 436 - 442.
Michael Hagmann, Nucleic Acids Res., Feb 1995; 23: 4978 - 4985.
C.Peter Verrijzer, Nucleic Acids Res., Dec 1992; 20: 6369 - 6375.
V¨¦ronique Goffin, Nucleic Acids Res., Aug 2005; 33: 4285 - 4310.

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

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