Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.
Saleh A. Bakheet, Toxicol. Sci., Feb 2007; 95: 436 - 442.
Michael Hagmann, Nucleic Acids Res., Feb 1995; 23: 4978 - 4985.
C.Peter Verrijzer, Nucleic Acids Res., Dec 1992; 20: 6369 - 6375.
V¨¦ronique Goffin, Nucleic Acids Res., Aug 2005; 33: 4285 - 4310.