OCT1 Antibody

Catalog Number:

33452

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P14859
NCBI Gene ID: 5451

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human OCT-1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total OCT-1 protein.

Applications:

WB IHC

Background:

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

Rikke H. Lewinsky, Hum. Mol. Genet., Dec 2005; 14: 3945 - 3953.
Harikrishna Nakshatri, J. Biol. Chem., Aug 1995; 270: 19613.
Mingfeng Liu, Eur. J. Biochem., May 2003; 270: 2274.
Vivek Mittal, Genes & Dev., Jul 1999; 13: 1807.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF