Product Datasheet  
OCT1 Antibody  
Catalog Number: 33452  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P14859
    NCBI Gene ID: 5451
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human OCT-1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100

  • other_names：  
  • NF-A1; OCT1; OTF-1; Octamer-binding transcription factor 1; PO21
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total OCT-1 protein.
  • Applications：  
  • WB IHC
  • Background：  

  • Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

    Rikke H. Lewinsky, Hum. Mol. Genet., Dec 2005; 14: 3945 - 3953.
    Harikrishna Nakshatri, J. Biol. Chem., Aug 1995; 270: 19613.
    Mingfeng Liu, Eur. J. Biochem., May 2003; 270: 2274.
    Vivek Mittal, Genes & Dev., Jul 1999; 13: 1807.




 
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