NM23 Antibody

Catalog Number:

33449

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P22392
NCBI Gene ID: 4831/654364

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human NM23.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NM23 protein.

Applications:

WB

Background:

Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (. Exhibits histidine protein kinase activity.

G Scambia, J. Clin. Oncol., Feb 1996; 14: 334 - 342.
S Kapitanovic, J. Clin. Pathol., Dec 2004; 57: 1312 - 1318.
R Amendola, J Natl Cancer Inst, Sep 1997; 89: 1300 - 1310.
Norio Iizuka, Cancer Res., Feb 1995; 55: 652 - 657.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF