Product Datasheet
NM23 Antibody
Catalog Number: 33449
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P22392
NCBI Gene ID: 4831/654364
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human NM23.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- EC 2.7.4.6; Metastasis inhibition factor nm23; NDK A; NDKA; NDP kinase A
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total NM23 protein.
- Background:
- Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (. Exhibits histidine protein kinase activity.
G Scambia, J. Clin. Oncol., Feb 1996; 14: 334 - 342.
S Kapitanovic, J. Clin. Pathol., Dec 2004; 57: 1312 - 1318.
R Amendola, J Natl Cancer Inst, Sep 1997; 89: 1300 - 1310.
Norio Iizuka, Cancer Res., Feb 1995; 55: 652 - 657.
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