MMP-9 Antibody

Catalog Number:

33446

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P14780
NCBI Gene ID: 4318

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human MMP-9.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MMP-9 protein.

Applications:

WB IHC

Background:

May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.

Martin Illemann, Mol. Cancer Res., May 2006; 4: 293 - 302.
Noemi Ramos-DeSimone, J. Biol. Chem., May 1999; 274: 13066.
Vandana Iyer, J. Cell Sci., Mar 2005; 118: 1185 - 1195.
Jon R. Backstrom, J. Neurosci., Dec 1996; 16: 7910.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF