Product Datasheet  
MMP-9 Antibody  
Catalog Number: 33446  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P14780
    NCBI Gene ID: 4318
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human MMP-9.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • 92 kDa gelatinase; 92 kDa type IV collagenase precursor; CLG4B; GELB; Gelatinase B
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total MMP-9 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.

    Martin Illemann, Mol. Cancer Res., May 2006; 4: 293 - 302.
    Noemi Ramos-DeSimone, J. Biol. Chem., May 1999; 274: 13066.
    Vandana Iyer, J. Cell Sci., Mar 2005; 118: 1185 - 1195.
    Jon R. Backstrom, J. Neurosci., Dec 1996; 16: 7910.




 
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