MMP-19 Antibody

Catalog Number:

33440

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q99542
NCBI Gene ID: 4327

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human MMP-19.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MMP-19 protein.

Applications:

WB IHC

Background:

Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.

Maud Jost, Cancer Res., May 2006; 66: 5234 - 5241.
Jan O. Stracke,J. Biol. Chem., May 2000; 275: 14809.
Simon Mauch, J. Immunol., Feb 2002; 168: 1244.
Thorsten Sadowski, Mol. Biol. Cell, Nov 2003; 14: 4569.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF