Product Datasheet  
MMP-19 Antibody  
Catalog Number: 33440  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q99542
    NCBI Gene ID: 4327
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human MMP-19.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • MATRIX METALLOPROTEINASE 18; FORMERLY; MMP18; FORMERLY; matrix metalloproteinase 19
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total MMP-19 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.

    Maud Jost, Cancer Res., May 2006; 66: 5234 - 5241.
    Jan O. Stracke,J. Biol. Chem., May 2000; 275: 14809.
    Simon Mauch, J. Immunol., Feb 2002; 168: 1244.
    Thorsten Sadowski, Mol. Biol. Cell, Nov 2003; 14: 4569.




 
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