MCL1 Antibody

Catalog Number:

33430

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q07820
NCBI Gene ID: 4170

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human MCL1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MCL1 protein.

Applications:

WB IHC

Background:

Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Alfredo De Biasio, J. Biol. Chem., Jun 2007; 10.1074.
Potchanapond Graidist, J. Biol. Chem., Sep 2004; 279: 40868 - 40875.
Kenichi Fujise, J. Biol. Chem., Dec 2000; 275: 39458.
Di Zhang, J. Biol. Chem., Sep 2002; 277: 37430 - 37438.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF