Product Datasheet  
MCL1 Antibody  
Catalog Number: 33430  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q07820
    NCBI Gene ID: 4170
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human MCL1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • EAT/MCL-1 protein; Induced myeloid leukemia cell differentiation protein Mcl-1; Myeloid cell leukemia sequence 1.;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total MCL1 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

    Alfredo De Biasio, J. Biol. Chem., Jun 2007; 10.1074.
    Potchanapond Graidist, J. Biol. Chem., Sep 2004; 279: 40868 - 40875.
    Kenichi Fujise, J. Biol. Chem., Dec 2000; 275: 39458.
    Di Zhang, J. Biol. Chem., Sep 2002; 277: 37430 - 37438.




 
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