Keratin 18 Antibody

Catalog Number:

33416

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P05783
NCBI Gene ID: 3875

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human Keratin 18.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Keratin 18 protein.

Applications:

WB IHC IF

Background:

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells By similarity. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Thomas M. Magin, J. Cell Biol., Mar 1998; 140: 1441.
Carlos Caul¨ªn, J. Cell Biol., Sep 1997; 138: 1379.
J Liao, J. Cell Biol., Dec 1995; 131: 1291.
Nam-On Ku, J. Clin. Invest., Jan 1997; 99: 19.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF