HDAC10 Antibody

Catalog Number:

33399

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q969S8
NCBI Gene ID: 83933

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human HDAC10.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HDAC10 protein.

Applications:

WB IHC

Background:

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Jenny J. Tong, Nucleic Acids Res., Mar 2002; 30: 1114 - 1123.
Hung-Ying Kao, J. Biol. Chem., Jan 2002; 277: 187 - 193.
Denise D. Fischer, J. Biol. Chem., Feb 2002; 277: 6656 - 6666.
Matthew H. Brush, J. Biol. Chem., Feb 2004; 279: 7685 - 7691.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF