Product Datasheet  
HDAC10 Antibody  
Catalog Number: 33399  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q969S8
    NCBI Gene ID: 83933
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human HDAC10.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Histone deacetylase 10; HD10;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total HDAC10 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

    Jenny J. Tong, Nucleic Acids Res., Mar 2002; 30: 1114 - 1123.
    Hung-Ying Kao, J. Biol. Chem., Jan 2002; 277: 187 - 193.
    Denise D. Fischer, J. Biol. Chem., Feb 2002; 277: 6656 - 6666.
    Matthew H. Brush, J. Biol. Chem., Feb 2004; 279: 7685 - 7691.



 
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