GRP78 Antibody

Catalog Number:

33395

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P11021
NCBI Gene ID: 3309

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human GRP78.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GRP78 protein.

Applications:

WB IHC IF

Background:

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.

Uma K. Misra, J. Biol. Chem., Oct 2002; 277: 42082 - 42087.
CA Clairmont, J. Biol. Chem., Feb 1992; 267: 3983 - 3990.
J Tooze, J. Cell Biol., Jul 1989; 109: 35.
Jong K. Yun, PNAS, Dec 1997; 94: 13903.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF