Product Datasheet  
GRP78 Antibody  
Catalog Number: 33395  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P11021
    NCBI Gene ID: 3309
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human GRP78.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500

  • other_names：  
  • BIP; GLUCOSE-REGULATED PROTEIN 78-KD; HEAT-SHOCK 70-KD PROTEIN 5; IMMUNOGLOBULIN HEAVY CHAIN-BINDING PROTEIN; heat shock 70kDa protein 5 (glucose-regulated protein
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total GRP78 protein.
  • Applications：  
  • WB IHC IF
  • Background：  

  • Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.

    Uma K. Misra, J. Biol. Chem., Oct 2002; 277: 42082 - 42087.
    CA Clairmont, J. Biol. Chem., Feb 1992; 267: 3983 - 3990.
    J Tooze, J. Cell Biol., Jul 1989; 109: 35.
    Jong K. Yun, PNAS, Dec 1997; 94: 13903.




 
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