GluR2/3 Antibody

Catalog Number:

33386

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q14832
NCBI Gene ID: 2912/2913

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human GluR2/3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GluR2/3 protein.

Applications:

WB IHC

Background:

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Akiko Momiyama, J. Physiol., May 2003; 549: 75 - 92.
Mako Narisawa-Saito, PNAS, Mar 1999; 96: 2461.
Karolina Wosik, Brain, Dec 2004; 127: 2636 - 2648.
Chong-Hyun Kim, PNAS, Sep 2001; 98: 11725.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF