Product Datasheet
GluR2/3 Antibody
Catalog Number: 33386
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q14832
NCBI Gene ID: 2912/2913
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human GluR2/3.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- GPRC1C; GRM3; MGR3; Metabotropic glutamate receptor 3 precursor; glutamate receptor metabotropic type 3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total GluR2/3 protein.
- Background:
- G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Akiko Momiyama, J. Physiol., May 2003; 549: 75 - 92.
Mako Narisawa-Saito, PNAS, Mar 1999; 96: 2461.
Karolina Wosik, Brain, Dec 2004; 127: 2636 - 2648.
Chong-Hyun Kim, PNAS, Sep 2001; 98: 11725.
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