Galectin 3 Antibody

Catalog Number:

33382

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P17931
NCBI Gene ID: 3958

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human Galectin 3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Galectin 3 protein.

Applications:

WB IHC IF

Background:

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis By similarity. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Miliyun G. Chiu, Am. J. Pathol., Dec 2006; 169: 1925 - 1938.
Luciana Kohatsu, J. Immunol., Oct 2006; 177: 4718 - 4726.
Brianna N. Stillman, J. Immunol., Jan 2006; 176: 778 - 789.
Julie Nieminen, J. Leukoc. Biol., Nov 2005; 78: 1127 - 1135.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF