Product Datasheet  
Galectin 3 Antibody  
Catalog Number: 33382  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P17931
    NCBI Gene ID: 3958
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human Galectin 3.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names：  
  • 35 kDa lectin; CBP 35; Carbohydrate binding protein 35; GALBP; Galactose-specific lectin 3
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Galectin 3 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis By similarity. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

    Miliyun G. Chiu, Am. J. Pathol., Dec 2006; 169: 1925 - 1938.
    Luciana Kohatsu, J. Immunol., Oct 2006; 177: 4718 - 4726.
    Brianna N. Stillman, J. Immunol., Jan 2006; 176: 778 - 789.
    Julie Nieminen, J. Leukoc. Biol., Nov 2005; 78: 1127 - 1135.




 
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