FAP-1 Antibody

Catalog Number:

33369

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q12884
NCBI Gene ID: 2191

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human FAP-1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FAP-1 protein.

Applications:

WB IHC

Background:

In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers.

Hendrik Ungefroren, J. Cell Sci., Aug 2001; 114: 2735.
Vladimir N. Ivanov, Mol. Cell. Biol., May 2003; 23: 3623 - 3635.
Vladimir N. Ivanov, J. Biol. Chem., Jan 2006; 281: 1840 - 1852.
T Sato, ience, Apr 1995; 268: 411 - 415.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF