Product Datasheet  
FAP-1 Antibody  
Catalog Number: 33369  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q12884
    NCBI Gene ID: 2191
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human FAP-1.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • DPPIV; FAPA; SEPRASE; fibroblast activation protein alpha subunit; integral membrane serine protease
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total FAP-1 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers.

    Hendrik Ungefroren, J. Cell Sci., Aug 2001; 114: 2735.
    Vladimir N. Ivanov, Mol. Cell. Biol., May 2003; 23: 3623 - 3635.
    Vladimir N. Ivanov, J. Biol. Chem., Jan 2006; 281: 1840 - 1852.
    T Sato, ience, Apr 1995; 268: 411 - 415.



 
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