Endostatin Antibody

Catalog Number:

33363

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P39060
NCBI Gene ID: 80781

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human endostatin.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total endostatin protein.

Applications:

IHC

Background:

COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.

Takayuki Furumatsu, J. Biochem. (Tokyo), Apr 2002; 131: 619 - 626.
Sonja Stahl, Genes Cells, Sep 2005; 10: 929 - 939.
NICOLAI MIOSGE, FASEB J, Oct 1999; 13: 1743.
Nicholas J. MacDonald, J. Biol. Chem., Jun 2001; 276: 25190 - 25196.

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF