Product Datasheet  
Endostatin Antibody  
Catalog Number: 33363  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P39060
    NCBI Gene ID: 80781
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human endostatin.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • COL18A1; ENDOSTATIN; collagen type XVIII alpha 1;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total endostatin protein.
  • Applications：  
  • IHC
  • Background：  
  • COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.

    Takayuki Furumatsu, J. Biochem. (Tokyo), Apr 2002; 131: 619 - 626.
    Sonja Stahl, Genes Cells, Sep 2005; 10: 929 - 939.
    NICOLAI MIOSGE, FASEB J, Oct 1999; 13: 1743.
    Nicholas J. MacDonald, J. Biol. Chem., Jun 2001; 276: 25190 - 25196.



 
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