CARD6 Antibody

Catalog Number:

33329

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q52LR2
NCBI Gene ID: 84674

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human CARD6.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CARD6 protein.

Applications:

WB IHC IF

Background:

This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.

Frank C. Kischkel, J. Biol. Chem., Nov 2001; 276: 46639 - 46646.
Daniela Sciaky, J. Immunol., Apr 2000; 164: 3806.
Vassiliki Poulaki, Invest. Ophthalmol. Vis. Sci., Jan 2005; 46: 358 - 366.
Lucia Ricci-Vitiani, J. Exp. Med., Nov 2004; 200: 1257 - 1266.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF