Product Datasheet
CARD6 Antibody
Catalog Number: 33329
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q52LR2
NCBI Gene ID: 84674
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human CARD6.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
- other_names:
- Caspase recruitment domain-containing protein 6; CARD6;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CARD6 protein.
- Background:
- This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.
Frank C. Kischkel, J. Biol. Chem., Nov 2001; 276: 46639 - 46646.
Daniela Sciaky, J. Immunol., Apr 2000; 164: 3806.
Vassiliki Poulaki, Invest. Ophthalmol. Vis. Sci., Jan 2005; 46: 358 - 366.
Lucia Ricci-Vitiani, J. Exp. Med., Nov 2004; 200: 1257 - 1266.
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