Bak Antibody

Catalog Number:

33326

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q16611
NCBI Gene ID: 578

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human Bak.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Bak protein.

Applications:

WB IHC IF

Background:

In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.

Takuma Uo, J. Biol. Chem., Mar 2005; 280: 9065 - 9073.
Pierre-Fran?ois Cartron, Mol. Cell. Biol., Jul 2003; 23: 4701 - 4712.
Joslyn K. Brunelle, J. Biol. Chem., Feb 2004; 279: 4305 - 4312.
Neil A. Jones, Mol. Pharmacol., May 1998; 53: 819.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF