Product Datasheet  
Bak Antibody  
Catalog Number: 33326  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q16611
    NCBI Gene ID: 578
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human Bak.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like 7 protein; BAK1; BAK
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Bak protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.

    Takuma Uo, J. Biol. Chem., Mar 2005; 280: 9065 - 9073.
    Pierre-Fran?ois Cartron, Mol. Cell. Biol., Jul 2003; 23: 4701 - 4712.
    Joslyn K. Brunelle, J. Biol. Chem., Feb 2004; 279: 4305 - 4312.
    Neil A. Jones, Mol. Pharmacol., May 1998; 53: 819.



 
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