p47 phox (Ab-345) Antibody

Catalog Number:

33293

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P14598
NCBI Gene ID: 653361

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human p47 phox around the phosphorylation site of serine 345 (P-Q-S(p)-P-G).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total p47 phox protein.

Applications:

WB IHC

Background:

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).

Volpp B.D., Proc. Natl. Acad. Sci. U.S.A. 86:7195-7199(1989).
Lomax K.J., Science 245:409-412(1989).
Rodaway A.R.F., Mol. Cell. Biol. 10:5388-5396(1990).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF