Product Datasheet  
p47 phox (Ab-345) Antibody  
Catalog Number: 33293  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P14598
    NCBI Gene ID: 653361
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human p47 phox around the phosphorylation site of serine 345 (P-Q-S(p)-P-G).
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-1; NCF-47K; NCF1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total p47 phox protein.
  • Applications：  
  • WB IHC
  • Background：  
  • NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).

    Volpp B.D., Proc. Natl. Acad. Sci. U.S.A. 86:7195-7199(1989).
    Lomax K.J., Science 245:409-412(1989).
    Rodaway A.R.F., Mol. Cell. Biol. 10:5388-5396(1990).



 
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