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CtBP1 (Ab-422) Antibody

Catalog Number:

33281
other_names: C-terminal binding protein 1; CTBP; EC 1.1.1.-;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q13363
NCBI Gene ID: 1487

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human CtBP1 around the phosphorylation site of serine 422 (A-P-S(p)-P-G).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CtBP1 protein.

Applications:

WB IHC

Background:

Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.

Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995).
Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999).
Boyd J.M., EMBO J. 12:469-478(1993).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

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