Product Datasheet  
CtBP1 (Ab-422) Antibody  
Catalog Number: 33281  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q13363
    NCBI Gene ID: 1487
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human CtBP1 around the phosphorylation site of serine 422 (A-P-S(p)-P-G).
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • C-terminal binding protein 1; CTBP; EC 1.1.1.-;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total CtBP1 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.

    Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995).
    Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999).
    Boyd J.M., EMBO J. 12:469-478(1993).




 
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