KNTC2 Antibody

Catalog Number:

33568

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O14777
NCBI Gene ID: 10403

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human KNTC2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KNTC2 protein.

Applications:

WB IF

Background:

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.

Chen Y., Mol. Cell. Biol. 17:6049-6056(1997).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Zheng L., Mol. Cell. Biol. 19:5417-5428(1999).

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF